(Source - The Onion)
Example 1: Heliocentrism
Since [the astronomer] cannot in any way attain to the true causes, he will adopt whatever suppositions enable the motions to be computed correctly from the principles of geometry for the future as well as for the past... these hypotheses need not be true nor even probable.
Example 2: Evolution
This textbook contains material on evolution. Evolution is a theory, not a fact, regarding the origin of living things. This material should be approached with an open mind, studied carefully and critically considered.
The top quote is a preface to Copernicus's On the Revolutions secretly prepended without Copernicus's knowledge by a Christian theologian in the 1540s.
The bottom quote is a preface to biology textbooks distributed in Atlanta public high schools in 2002.
That gives us a Δt of approximately 460 years across which the complexity of the anti-science argument has gone from:
"...[T]hese hypotheses need not be true nor even probable."to:
"[This scientific idea] is a theory, not a fact."
So, how does one succeed as an anti-scientist? Just keep repeating the same thing over and over again for centuries while the world around you changes ever faster.